Viral Vector Services
Adenovirus Downstream Processes
We offer a comprehensive and GMP-compliant downstream processing platform for adenovirus vectors, ensuring the highest quality for your gene therapy or vaccine projects.
Our specialized downstream processes enhance efficiency and purity, crucial for gene therapy and vaccine development. Benefit from comprehensive solutions that streamline production and ensure top-quality results.
Our process includes:
- Tangential flow filtration (TFF) for efficient removal of impurities and buffer exchange
- A capture step to purify and concentrate adenovirus vectors
- Polishing chromatography to achieve optimal purity
- Final concentration and formulation using TFF or dialysis for smaller volumes
- Thorough analysis of the Drug Substance to meet stringent regulatory requirements
For small-scale production, we provide fast gradient ultracentrifugation-based purification, tailored for clarified adenovirus vector harvests. To ensure sterility, the final filtration step is conducted using a 0.2 µm filter, delivering a high-quality product ready for clinical or commercial use.
With you all the way…
together, making advanced biologics, and tomorrow’s life-transforming therapies.
We deliver unparalleled end-to-end development and manufacturing services for all protein expression systems and viral vectors, both for Drug Substances and Drug Products, from pre-clinical to clinical development and commercial phases.
We support our customers wherever they are on their journey, from early-stage development to commercialization. We are passionate, precise, and always close, together, making advanced biologics and tomorrow’s life-transforming therapies.
Pre-Clinical
Phase I
Phase II
Phase III
Commercial