Viral Vector Services
AAV Platform
A comprehensive platform for AAV gene therapy development and manufacturing.
AAV Platform is a robust and reliable platform solution for AAV manufacturing. From in-house plasmid design and process development to GMP manufacturing, aseptic fill and finish, and analytical testing, our platform ensures high-quality, scalable production tailored to your needs.
With cutting-edge technology and deep expertise, AAV Platform streamlines the journey from preclinical research to commercial-scale production, supporting the advancement of transformative gene therapies.
- From Design of Experiment (DoE) process development to clinical and commercial GMP manufacturing
- Efficient and controlled upscaling of AAV vector production
- No royalties applied
- Full freedom to operate
In-house Plasmids
- Freedom to operate, off-the-shelf plasmids
- High quality, high yield
- Backbones suitable for clinical trials
- pHelper 100% free of fiber and hexon genes
Outstanding cell line
- In-house HEK293 suspension cell line
- Single cell growth, easy to transfect
- High cell density, short doubling time
- High-titer. high full/empty ratio
Upstream process
- Robust and scalable upstream process
Downstream process
- Design of Experiments (DoE) for novel capsids
- Efficient enrichment of full capsids
- Comprehensive purification solutions: TFF, Affinity and IEX Chromatography
- Ultracentrifugation, if requested
Aseptic Fill and Finish
- Formulation and final drug product manufacturing including CCI testing
- Packaging and labelling
- QP release of IMP
Quality Control & Quality Assurance
- Comprehensive in-house capabilities with 40+ assays
- In-Process Control (IPC) and release testing
- Full/empty measurements
- Stability studies including analysis for vector stability
With you all the way…
together, making advanced biologics, and tomorrow’s life-transforming therapies.
We deliver unparalleled end-to-end development and manufacturing services for all protein expression systems and viral vectors, both for Drug Substances and Drug Products, from pre-clinical to clinical development and commercial phases.
We support our customers wherever they are on their journey, from early-stage development to commercialization. We are passionate, precise, and always close, together, making advanced biologics and tomorrow’s life-transforming therapies.
Pre-Clinical
Phase I
Phase II
Phase III
Commercial