Single-use systems (SUS) are disposable, pre-sterilized bioprocessing components and equipment used in biopharmaceutical manufacturing to perform unit operations without the need for cleaning and sterilization between batches. These systems typically include single-use bioreactors, tubing, bags, filters, and mixing systems. Single-use technologies are widely used in upstream and downstream processing to improve process flexibility, reduce cross-contamination risk, and increase manufacturing efficiency.