A fusion protein is a recombinant protein engineered by joining two or more gene sequences that encode distinct protein domains or functional regions, resulting in a single chimeric molecule with combined properties. Fusion proteins are widely used as biopharmaceutical therapeutics — including Fc-fusion proteins, antibody-drug conjugates (ADCs), and receptor-fusion proteins — as well as purification tags and reporter systems in bioprocessing. Their design enables improved pharmacokinetics, target specificity, stability, and therapeutic efficacy compared to their individual components.
